Heatmap depicting the RNA data of Jia and Sharma
Heatmap depicting the RNA data of TCGA
Heatmaps depicting the Feature data of Jia dataset
Heatmaps depicting the Feature data of LUAD dataset
Heatmaps depicting the Feature data of LUSC dataset
Heatmaps depicting the Feature data of CRC dataset
Heatmaps depicting the Feature data of SKCM dataset
Heatmaps depicting the Feature data of PBMC dataset
## $Jia
## RNAseq
## 68.23396
##
## $Jia
## RNAseq
## Factor1 26.109267
## Factor2 15.140792
## Factor3 9.273429
## Factor4 6.395170
## Factor5 4.921713
## Factor6 3.645070
## Factor7 2.840035
## $Jia
## Immune cells quantification Pathway scores
## 31.88450 75.50269
## Transcription factors
## 81.80199
##
## $Jia
## Immune cells quantification Pathway scores Transcription factors
## Factor1 9.04474250 25.619542 40.579562
## Factor2 16.46881862 13.041630 6.059506
## Factor3 4.16318229 12.482454 14.195675
## Factor4 0.48687257 10.815804 9.561976
## Factor5 1.12789197 5.140326 6.429715
## Factor6 0.61185598 5.309700 2.828404
## Factor7 0.01614819 2.168045 3.477739
Heatmap depicting the MOFA results of Jia dataset
## $Jia
## RNAseq
## 63.49116
##
## $Sharma
## RNAseq
## 53.91061
##
## $Jia
## RNAseq
## Factor1 25.554560
## Factor2 11.992019
## Factor3 1.282114
## Factor4 10.905898
## Factor5 6.423837
## Factor6 3.041194
## Factor7 4.252318
##
## $Sharma
## RNAseq
## Factor1 22.7049103
## Factor2 11.1926794
## Factor3 13.4522387
## Factor4 2.9412181
## Factor5 1.0376639
## Factor6 3.5540332
## Factor7 0.9137955
## $Jia
## Immune cells quantification Pathway scores
## 21.34774 71.64954
## Transcription factors
## 78.32020
##
## $Sharma
## Immune cells quantification Pathway scores
## 20.35690 58.88863
## Transcription factors
## 74.50499
##
## $Jia
## Immune cells quantification Pathway scores Transcription factors
## Factor1 9.4420220 24.238854 37.373011
## Factor2 0.7418870 9.503687 15.918343
## Factor3 10.7504973 12.705553 5.856245
## Factor4 0.5690629 6.457295 8.918773
## Factor5 0.2254012 10.236809 4.819569
## Factor6 0.7581855 2.443406 3.351741
## Factor7 0.1695355 3.968168 4.310816
##
## $Sharma
## Immune cells quantification Pathway scores Transcription factors
## Factor1 8.711650804 36.4894661 45.074942
## Factor2 -0.464040829 2.8603389 11.397810
## Factor3 6.928408588 1.4788415 1.362861
## Factor4 2.099729742 9.6558138 9.012147
## Factor5 1.077867091 7.5636400 1.553084
## Factor6 0.378333699 2.2220397 5.433451
## Factor7 0.003460828 0.6104246 3.547656
Heatmap depicting the MOFA results of RNA-seq analysis of the Jia-Sharma dataset
## $LUAD
## RNAseq
## 36.04769
##
## $LUAD
## RNAseq
## Factor1 10.578338
## Factor2 7.755154
## Factor3 4.574471
## Factor4 4.459151
## Factor5 3.215678
## Factor6 3.186303
## Factor7 2.584139
## $LUAD
## Immune cells quantification Pathway scores
## 24.20549 40.10403
## Transcription factors
## 61.79617
##
## $LUAD
## Immune cells quantification Pathway scores Transcription factors
## Factor1 10.551752 8.008269 22.508832
## Factor2 1.337535 9.847336 14.387137
## Factor3 2.920561 5.496181 12.589275
## Factor4 6.742311 6.216552 1.840613
## Factor5 1.266392 7.147005 6.152219
## Factor6 1.386933 3.388691 4.318094
Heatmap depicting the MOFA results of LUAD dataset
## $LUSC
## RNAseq
## 39.59177
##
## $LUSC
## RNAseq
## Factor1 12.830726
## Factor2 7.306695
## Factor3 5.448373
## Factor4 4.717565
## Factor5 3.938002
## Factor6 3.281719
## Factor7 2.160142
## $LUSC
## Immune cells quantification Pathway scores
## 25.91362 54.33659
## Transcription factors
## 77.37114
##
## $LUSC
## Immune cells quantification Pathway scores Transcription factors
## Factor1 13.8213517 13.467181 32.2411668
## Factor2 3.9561132 10.432106 15.5878992
## Factor3 5.2129073 6.257736 5.8180351
## Factor4 0.2552738 4.396189 8.0073593
## Factor5 1.3935745 7.104439 2.8584741
## Factor6 0.6314688 2.195804 5.3377074
## Factor7 1.4115221 2.630566 0.6968012
Heatmap depicting the MOFA results of LUSC dataset
## $NSCLC
## RNAseq
## 41.78628
##
## $NSCLC
## RNAseq
## Factor1 17.725410
## Factor2 7.082743
## Factor3 5.370592
## Factor4 4.021149
## Factor5 3.057802
## Factor6 2.840507
## Factor7 2.154332
## $NSCLC
## Immune cells quantification Pathway scores
## 19.92243 52.70010
## Transcription factors
## 74.02841
##
## $NSCLC
## Immune cells quantification Pathway scores Transcription factors
## Factor1 10.6849023 9.436347 24.831503
## Factor2 0.8309582 12.608703 6.934714
## Factor3 1.5619903 5.351272 11.795849
## Factor4 1.7179859 3.821442 8.524851
## Factor5 0.7268656 3.873664 4.983322
## Factor6 1.6017107 4.304303 3.309388
## Factor7 1.3362683 2.999443 2.449172
Heatmap depicting the MOFA results of NSCLC dataset
## $CRC
## RNAseq
## 40.32648
##
## $CRC
## RNAseq
## Factor1 17.251105
## Factor2 9.149151
## Factor3 5.121999
## Factor4 3.429345
## Factor5 2.265343
## Factor6 1.888763
## Factor7 1.751464
## $CRC
## Immune cells quantification Pathway scores
## 22.32748 46.53928
## Transcription factors
## 66.10702
##
## $CRC
## Immune cells quantification Pathway scores Transcription factors
## Factor1 13.4793838 19.074814 31.329550
## Factor2 2.6458338 9.873936 16.205573
## Factor3 2.8161162 5.304654 9.593038
## Factor4 2.2873662 4.936317 3.522675
## Factor5 1.0840800 4.071545 2.802916
## Factor6 0.0147043 3.278018 2.653271
Heatmap depicting the MOFA results of CRC dataset
## $SKCM
## RNAseq
## 40.06379
##
## $SKCM
## RNAseq
## Factor1 11.572346
## Factor2 8.838881
## Factor3 6.716767
## Factor4 4.677261
## Factor5 4.149576
## Factor6 2.745333
## Factor7 1.589064
## $SKCM
## Immune cells quantification Pathway scores
## 25.48666 57.29829
## Transcription factors
## 76.42455
##
## $SKCM
## Immune cells quantification Pathway scores Transcription factors
## Factor1 16.0441325 19.908703 38.866783
## Factor2 1.4521253 9.139358 13.493822
## Factor3 1.3222194 8.842419 6.355452
## Factor4 3.4132786 9.520523 2.666744
## Factor5 1.5271311 2.797199 8.710657
## Factor6 0.6765548 5.478299 3.719744
## Factor7 0.6073407 2.133412 2.213119
Heatmap depicting the MOFA results of SKCM dataset
## $PBMC
## RNAseq
## 76.49658
##
## $PBMC
## RNAseq
## Factor1 63.966862
## Factor2 8.426346
## Factor3 2.597099
## Factor4 1.506278
## $PBMC
## Immune cells quantification Pathway scores
## 64.53760 69.49374
## Transcription factors
## 72.75441
##
## $PBMC
## Immune cells quantification Pathway scores Transcription factors
## Factor1 5.756328e+01 5.747104e-04 10.333415
## Factor2 8.467576e-04 2.469436e+01 25.470690
## Factor3 2.633135e+00 1.634614e+01 21.055315
## Factor4 5.061628e-01 1.485045e+01 7.471381
## Factor5 3.534691e+00 1.088466e+01 2.210367
## Factor6 2.994938e-01 2.717556e+00 6.213241
Heatmap depicting the MOFA results of PBMC dataset
Heatmap depicting the correlation of all factors of all models based on feature data. Only significant relations (p<0.001) are shown.
Heatmap depicting the results of the feature analysis of all datasets.